品牌:美國 NewEast Biosciences
貨號: 26904
抗原:Full Recombinant active RhoA
規格:30 微升
產品全名:Anti-RhoA-GTP Mouse Monoclonal Antibody
應用: IP, IHC, IF
種屬反應性的選擇:Human, Mouse and Rat
物種/宿主:Mouse
描述: Anti-RhoA-GTP Mouse Monoclonal Antibody
背景介紹: Small GTPases are a super-family of cellular signaling regulators. RhoA belongs to the Rho sub-family of GTPases. Rho proteins play critical roles in many actin cytoskeleton- dependent processes including platelet aggregation, cell motility, contraction, and cytokinesis. It regulates the formation of stress fibers and focal adhesions in fibroblasts and Ca 2+ sensitivity of smooth muscle contraction.
免疫原: Recombinant full length protein of active RhoA
經過測試的應用: IP, IHC,IF
推薦稀釋比: IP: 1 μg for 1~2 mg total cellular proteins IHC, IF: 1:50-1:250
濃度: 1 mg/ml
宿主: Mouse
形式: Liquid
克隆性: Monoclonal
亞型: IgG2b
純度: Purified from ascites
防腐劑: No
成分: PBS (without Mg 2+ and Ca 2+ ), pH 7.4, 150 mM NaCl, 50% glycerol
種屬反應性: Anti-RhoA monoclonal antibody recognizes active RhoA from vertebrates.
儲存條件: Store at -20°C. Avoid repeated freezing and thawing
Immunoprecipitation/Western Blot:
IP/WB Analysis of Active RhoA Protein.Purified recombinant RhoA proteins were loaded with GDP (lane 1) or GTPγS (lane 2). These proteins were immunoprecipitated with anti-RhoA-GTP monoclonal antibody (Cat. # 26904). After SDS/PAGE, the membrane filter was probed with anti-RhoA mouse monoclonal antibody (Cat. # 26007).
武漢費斯德生物科技有限公司是美國NewEast Biosciences在中國的辦事處，也是目前所有產品國內經銷處。
目前客戶使用產品發表超過1000谷歌學術文獻，其中論文分布排名前50刊物上。
NewEast Biosciences 在十二年前率先研發倆種獨特的抗體。這倆種抗體僅僅識別活性的GTP酶或者突變的Oncogene。 GTP酶涉及(1)響應細胞表面受體**的信號轉導，包括跨膜受體，例如介導味覺、嗅覺和視覺的那些，（2）核糖體的蛋白質生物合成，（3）調節細胞分化、增殖、分裂和運動，（4）蛋白質通過膜的易位，（5）細胞內囊泡的運輸，以及囊泡介導的分泌和攝取，通過GTP酶控制囊泡外殼組裝。Oncogene側是誘發癌癥的基因。
更多產品類目和技術資料可查看：武漢費斯德生物官網。
